30 research outputs found
EVALUATION OF GENOTOXICITY PROFILE OF JASADA BHASMA (A ZINC-BASED MINERAL FORMULATION) IN SWISS ALBINO MICE
Get PDFĂ‚Â Ă‚Â Objective: Genotoxicity is regarded as one of the potential risk factors for causing pathological diseases. It was confirmed that many chemicals have the mutagenic activity which leads to cancer. A compound which interacts with genetic material DNA and shows adverse effects by altering its structure or function is referred to as genotoxic.Methods: The present study involved 40 Swiss albino mice weighing between 25 and 30 g body weights categorized into four different groups. Group-I (normal control) received 0.5% carboxymethyl cellulose as vehicle. Group-II (toxicant control) received 40 mg/kg/body weight cyclophosphamide on the 28th day. Group-III and IV received test drug JB 15.6 mg/kg and 78 mg/kg, respectively, for 28 consecutive days. Blood samples were collected and processed for evaluating by comet assay. The animals were sacrificed and collected the bone marrow from both the femur for chromosomal aberration and micronuclei assay.Results: JB administered at two different dose levels did not show any significant changes in the comet assay parameters, no micronucleus was found and did not produce any chromosomal aberrations both numerically and structurally when compared to positive test control group.Conclusion: The genotoxicity evaluation of JB did not show any chromosomal aberrations and presence of micronucleus. Thus, the safety data will refine therapeutic utility of JB encouraging their rationale use and translate into greater and broader utilization of JB
Edible mushroom: occurrence, management and health benefits
Get PDFOwing to medicinal and nutraceutical properties, mushrooms have been consumed worldwide for many years. They are valued for their unique flavor, texture, and versatility in cooking. Numerous species of edible mushrooms have different habitats, ecological niches, and growth patterns. In a vegetarian diet, mushrooms have been preferred and widely accepted over a non-vegetarian one because of their low-calorie, high-protein content and their good source of carbohydrates and lipids. Edible mushrooms provide various macronutrients, micronutrients, minerals, and vitamins. Bioactive compounds extracted from different species of mushrooms exhibit various medicinal properties, such as antitumor, antioxidant, hypocholesterolemic, antiallergic, anti-inflammatory, and hypoglycemic effects. These properties are mainly due to polysaccharides like β-glucan, polyphenols like phenolic acids and flavonoids, carotenoids, and vitamins. Edible mushrooms are also potential prebiotics and are beneficial for human gut health. Secondary metabolites extracted from edible mushrooms are used to develop drugs to treat chronic diseases.In conclusion, edible mushrooms contain essential food supplements and versatile food sources that provide numerous health benefits. Effective management of edible mushroom production is crucial to ensure their continued availability, quality, and sustainability. The study of edible mushrooms and their health benefits continues to be an area of active research, and additional benefits will likely be further discovered
Presence 5 for Racial Justice Workshop: Fostering Dialogue Across Medical Education to Disrupt Anti-Black Racism in Clinical Encounters
Get PDFIntroduction: Anti-Black racism has strong roots in American health care and medical education. While curricula on social determinants of health are increasingly common in medical training, curricula directly addressing anti-Black racism are limited. Existing frameworks like the Presence 5 framework for humanism in medicine can be adapted to develop a novel workshop that promotes anti-racism communication. Methods: We performed a literature review of anti-racism collections and categorized anti-racism communication practices using the Presence 5 framework to develop the Presence 5 for Racial Justice Workshop. Implementation included an introductory didactic, a small-group discussion, and a large-group debrief. Participants evaluated the workshop via an online survey, and we analyzed the resulting qualitative feedback. Results: A total of 17 participants took part in two workshops, with nine of the participants responding to the evaluation survey. Themes that emerged from survey responses included strengths of and improvements for the workshop structure (protected time for anti-racism discussion, dialogue between learners and faculty) and content (specific phrases and language, practicing self-reflection). Discussion: The workshop provides participants with a semistructured discussion around the five anti-racism communication practices. Barriers to implementation include incorporating the workshop into existing curricula and ensuring diverse learners. Barriers to evaluating the workshop include the low survey response rate. Recommendations to improve the workshop include using case-based discussion and varying the workshop structure according to institutional needs. Next steps include an implementation study to evaluate the acceptability, feasibility, and effectiveness of the workshop
Humanism in telemedicine: Connecting through virtual visits during the COVID-19 pandemic
Full text linkThe COVID-19 pandemic is spurring the massive deployment of telemedicine to prevent risk of infection and address healthcare workforce demands. In primary care, many visits have shifted from in-person to telemedicine, introducing a potential barrier to the human connection that is central to clinical care. We adapted existing frameworks that seek to foster humanism in clinical care-the Four Habits Model and Presence 5-to the virtual care context. Reconceptualizing these frameworks to video visits in particular yields strategies for four phases of the visit - (1) Before the Visit: Set up for Success, (2) Beginning the Visit: Establish a Connection, (3) Throughout the Visit: Invest in the Relationship and the Patient's Story, and (4) Completing the Visit: End on a Meaningful Note. Adopting explicit humanistic practices can help clinicians foster meaningful connections with patients through video visits amidst this challenging pandemic and in the future as telemedicine becomes more widely integrated into clinical care.This study was supported by a grant from the Gordon and Betty Moore Foundation (#6382; PIs Donna Zulman and Abraham Verghese). Megha Shankar is supported by a VA Office of Academic Affairs Advanced Fellowship in Health Services Research. The views expressed herein are those of the authors and do not necessarily reflect the views of the Department of Veterans Affairs, the Gordon and Betty Moore Foundation, or Stanford University School of Medicine.https://deepblue.lib.umich.edu/bitstream/2027.42/154738/1/Shankar article file.pdfDescription of Shankar article file.pdf : Main articl
Antibiotic prescribing in two private sector hospitals; one teaching and one non-teaching: A cross-sectional study in Ujjain, India
Full text linkPresence 5 for Racial Justice Workshop: Fostering Dialogue Across Medical Education to Disrupt Anti-Black Racism in Clinical Encounters.
No full textA Review Study on Healthcare Management
No full textHealthcare is an integral part of the mankind development. Managing the Healthcare sector has its own sphere of challenges. There are players in the market who have been contributing quit well towards healthcare. These Entrepreneurs who enter the field of Healthcare product demonstrate a unique feature of commercialisation with the moral attributes of producing product that protects the health interest of People. The Healthcare Entrepreneurship which entails to provide the solutions to the Healthcare Needs of the Society has been a great advent in the society since ages. Healthcare Startups have also gained momentum with time. The Healthcare starts ups in the Nation have been adopting innovative practices to solve needs of people. Healthcare Management supports this momentum and involves supervising medical services and facilities to ensure efficient patient care through tasks like planning, organizing, staffing, and resource allocation.
This review paper is a descriptive article attempted by collecting data through the Secondary sources. The study aims to understand the concept & essence of Healthcare Management. It further aims to gather insights on the Healthcare Management through structured review of literature. The authors have contributed a Healthcare Management recommendation based on the review study. The study depicts the knowledge on Healthcare Management and the literary effort can serve as Literature for further studies. The authors have considered Healthcare Management aspects at large rather any specific wing of Healthcare sector. Hence this may be the limitations of the study. The inferences drawn from the study may be indicative in nature rather exhaustive
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Moving beyond inquiry: a secondary qualitative analysis on promoting racial justice in clinical care
No full textBackgroundAnti-Black racism is prevalent in medicine, and anti-racism training is needed in medical education. One such training is the Presence 5 for Racial Justice (P5RJ) Curriculum which covers evidence-based anti-racism communication strategies that promote health equity for Black patients. The P5RJ Curriculum was developed using feedback from clinicians and trainees with diversity, equity, and inclusion (DEI) experience. In this study, we identify themes in recommended anti-racism language and phrases that surveyed clinicians and trainees use to promote racial justice and health equity in clinical care for Black patients.MethodsSecondary analysis of survey responses to identify themes in qualitative data.DatasetSurvey responses of specific phrases for anti-racism communication based on P5RJ Curriculum feedback.Population studiedN = 50 respondents (27 clinicians, 17 medical trainees, 6 unreported) recruited through convenience sampling and listservs of clinicians with DEI experience. An inductive qualitative analysis was performed on survey responses to identify emerging themes.ResultsEmerging themes from survey responses reflected four communication practices: "Inquiry" was the predominant practice (59%), followed by "Empathy" (25%), "Statements of Allyship" (9%), and "Self-Accountability" (8%).ConclusionInquiry and empathy may be predominant communication practices when addressing anti-Black racism in medicine. There is an opportunity to expand anti-racism communication tools with statements of self-accountability and allyship. Future research is necessary to analyze the patient voice on clinician communication practices that promote anti-racism in clinical care
